sever, rip, break off, blindside, separate, cast off/out, rock, drop, split, sear, shatter, break free, slough off, bolt, rend, attack, buckle, burst, flare, explode, fragment, betray, divide, rescind, abandon, derail, cut off, doom, plummet, disintegrate, crumble, break up, reel, reject, spurn, fizzle, fail, botch, refuse, rankle, stab in the back, sour, erode, leave behind, alienate, despise, ostracize, tear apart, divorce, exile, fracture, splinter, pull back/away, disinherit, part (ways), spin out, cancel (a wedding), detonate, cut ties with (one's family), cuckold
assault, stab, sicken, curse, slur, swear, insult, humiliate, disgust, nauseate, turn off, outrage, wound, antagonize, rub the wrong way, offend, gross out, tread on someone's toes, affront, hurt someone's feelings, add insult to injury, spit daggers, rub salt in a wound, blaspheme, cuss, ruffle someone's feathers
jolt, worry, stun, startle, scramble, distract, cloud, hoodwink, mislead, fool, vex, confuse, confound, stupefy, nonplus, disorient, bewitch, overwhelm, disturb, stump, puzzle, jumble, discombobulate, shock, flummox, astound, unnerve, flabbergast, daze, faze, floor, alarm, destabilize, scare, alert, distress, unsettle, disconcert, discomfit, perturb, jangle, throw someone off balance, test (someone's assumptions), discompose, subject to
jar, gnaw, jolt, bother, rattle, agitate, startle, blot out, pique, muddle, baffle, vex, trouble, trip up, disturb, boggle, astonish, dumbfound, unnerve, upset, rankle, jostle, inflame, horrify, alienate, appall, gall, aggravate, exasperate, disconcert, discomfit, mortify, irritate, drive to distraction, get someone's goat, peeve, try someone's patience, rub the wrong way, miff, jangle, make someone's blood boil, evoke (a strong reaction), get someone's dander up, ruffle someone's feathers, make someone's hackles rise, discomfort