hollow out, squash, quash, thin, water down, beat down, weaken, endanger, jeopardize, encumber, impair, undermine, sap, suck out, incapacitate, exhaust, erode, blunt, drain (of vitality), enervate, starve, grind down, tax (one's reserves), hit someone hard, wind (one from exertion), tire someone out, debilitate, fatigue, wear out/down, devitalize, eat away, chip away at, weary, defang