chuck, stoop, slouch, slump, shrug, slacken, skip, submit, surrender, weaken, cut short, abdicate, quit, plummet, fall, opt out, yield, come to terms with, give up, accede, resign oneself, hit bottom, bail out, abandon (hope), mope, brood, capitulate, lose ground, acquiesce, isolate oneself, forgo, cede, drop out, sink into (depression), lose hope, stop trying/working, accept (defeat), sever (contact), throw in the towel, default (on one's payments), raise (a white flag), hang (one's head), drown, fall off (in one's duties), let go (of one's dreams), step down/away, slide into depression, give away
cut, slink, retreat, elude, evade, shy away, recede, vanish, disappear, flee, dodge, withdraw, shut down, avoid, leave, rupture, escape, sulk, turn away, isolate oneself, get drunk, get out of, insulate oneself (from the challenges of life), drop out, cut oneself off, run away, turn back, break away, turn to (drugs), back away/down, pull back/out, skip out, drop out of, quit (one's job), talk one's way out of, put in two weeks' notice, sleep, lock oneself in (a room), keep to oneself